The route of exposure significantly influences the physiological effects of toxins. Common routes include inhalation, ingestion, and dermal absorption. Inhalation can rapidly affect the lungs and enter the bloodstream, leading to systemic effects. Ingestion primarily impacts the gastrointestinal tract and liver, while dermal exposure might result in localized skin effects or systemic absorption if the skin barrier is compromised. Understanding the route of exposure helps in predicting and managing toxic effects.