What Strategies Are Used to Minimize Toxicity in Antibiotic Review Programs?
Several strategies are employed to minimize toxicity:
1. Dose Optimization: Adjusting the dose based on pharmacokinetic and pharmacodynamic principles to achieve effective concentrations with minimal toxicity. 2. Therapeutic Drug Monitoring: Regular measurement of drug levels in the blood to ensure they are within the therapeutic range. 3. Alternative Therapies: Using non-antibiotic treatments when appropriate to reduce the risk of toxicity. 4. Patient-Specific Approaches: Customizing treatment based on individual patient factors, such as renal function and potential drug interactions.
