What Techniques are Used to Visualize Tissue Changes?
Several imaging techniques are employed to visualize tissue changes, each with its unique advantages:
Histopathology: This traditional method involves staining tissue sections and examining them under a microscope, allowing for the identification of structural changes such as necrosis, inflammation, or fibrosis. Electron Microscopy: This provides high-resolution images of cellular ultrastructure, revealing subcellular changes induced by toxicants. Magnetic Resonance Imaging (MRI): MRI offers non-invasive, detailed images of soft tissues, useful for detecting changes in organ structure and function. Computed Tomography (CT): CT scans provide cross-sectional images of tissues, helpful in assessing gross morphological changes. Fluorescence Imaging: This technique uses fluorescent probes to visualize specific molecular or cellular structures in tissues.
