What Types of Studies are Conducted in Pre-Market Testing?
Pre-market testing involves several types of studies to evaluate different aspects of toxicity:
In vitro studies: These are conducted in a controlled laboratory environment using cell cultures to assess cytotoxicity and other effects without using live animals. In vivo studies: These involve testing on live animals to study the systemic effects and absorption, distribution, metabolism, and excretion (ADME) of the substance. Computational models: These are used to predict toxicity using computer-based algorithms and databases, reducing the need for animal testing.
