Which Substances Are Commonly Associated with Myocardial Toxicity?
Several substances are known to have toxic effects on the myocardium:
- Anthracyclines, like doxorubicin, are chemotherapeutic agents that can lead to dose-dependent cardiac damage. - Cocaine is a stimulant that can cause acute myocardial infarction and chronic cardiomyopathy. - Alcohol abuse can lead to alcoholic cardiomyopathy, characterized by dilated and weakened heart muscle. - Heavy metals, such as lead and arsenic, can induce myocardial injury through oxidative stress and interference with cellular function.