Several drugs and chemicals can induce polydipsia. For example, lithium, a medication used to treat bipolar disorder, can cause nephrogenic diabetes insipidus, leading to increased thirst and urination. Amphetamines and other stimulants can also result in polydipsia due to their effects on the central nervous system. Furthermore, exposure to heavy metals such as lead and mercury can affect renal function, potentially leading to excessive thirst.
