Several toxins are known to cause bradycardia, including:
- Beta-blockers: These medications, used to treat high blood pressure and heart conditions, can cause bradycardia if taken in excessive amounts. - Calcium channel blockers: Overdose of these drugs, often prescribed for hypertension and angina, can lead to severe bradycardia. - Organophosphates: Commonly found in pesticides, these chemicals inhibit acetylcholinesterase, leading to increased vagal tone and bradycardia. - Digitalis: Derived from the foxglove plant, this cardiac glycoside can cause bradycardia due to its effects on the conduction system. - Opioids: High doses of opioids can depress the central nervous system and lead to bradycardia.