Several key organizations are responsible for regulatory actions in toxicology worldwide. In the United States, the Environmental Protection Agency (EPA) plays a crucial role, particularly in the regulation of pesticides and industrial chemicals. The Food and Drug Administration (FDA) oversees the safety of food, pharmaceuticals, and cosmetics. Internationally, the European Chemicals Agency (ECHA) manages chemical regulations in the European Union under the REACH framework. Similarly, the World Health Organization (WHO) provides guidelines for chemical safety at a global level.
