Why are CYP450 Inhibitors Important in Toxicology?
CYP450 inhibitors are crucial in toxicology because they can significantly affect drug metabolism and disposition. Understanding their role helps in anticipating potential drug-drug interactions, adverse drug reactions, and toxic effects. For instance, if a patient is taking multiple drugs, one of which is a CYP450 inhibitor, it may lead to increased plasma levels of other drugs, causing toxicity.
