Why are Phase II Reactions Important in Toxicology?
Phase II reactions are essential in toxicology because they enhance the water solubility of potentially harmful compounds, facilitating their excretion via urine or bile. By doing so, these reactions help prevent the accumulation of toxic substances in the body, thereby minimizing the risk of adverse effects and toxicity. Additionally, effective Phase II metabolism is crucial for the detoxification of many drugs, environmental chemicals, and endogenous metabolites.
