The application of the 3Rs in toxicology is essential for both ethical and scientific reasons. Ethical concerns about animal welfare have led to stricter regulations and public scrutiny, making the 3Rs a necessary practice in laboratory environments. Scientifically, the 3Rs encourage innovation and the use of cutting-edge technologies that can lead to more accurate and reproducible results. For example, QSAR models are used to predict the toxicity of compounds without animal testing, offering insights into chemical behavior in biological systems.
