Why are these populations more susceptible to toxicants?
Sensitivity to toxicants can arise from several factors:
Biological Factors: Differences in metabolism, absorption, distribution, and excretion of chemicals can influence susceptibility. For example, children have higher respiratory rates, leading to greater inhalation exposure. Developmental Factors: During critical periods of growth, such as fetal development or early childhood, exposure to toxicants can disrupt normal development. Physiological Factors: Changes in body composition and organ function, especially in the elderly, can alter the body's ability to handle toxic substances.
