Why is Immunohistochemistry Important in Toxicology?
IHC is crucial in toxicology for several reasons:
Detection of Biomarkers: IHC can identify biomarkers of exposure, effect, and susceptibility. These biomarkers can indicate the presence of toxic substances and their impact on the body. Pathological Assessment: It allows for the examination of tissue pathology, which is essential in understanding how toxins affect specific tissues or organs. Mechanistic Insights: IHC can provide insights into the mechanisms of toxicity by visualizing the distribution and localization of toxicants and their metabolites within tissues.
