The consideration of species specificity is essential in toxicology for several reasons. Primarily, it ensures the accurate prediction of toxicity in humans based on animal studies. Without acknowledging these differences, there can be significant misinterpretations of the data, potentially leading to either overestimations or underestimations of human risk. Additionally, it is crucial for the ethical use of animals in research; knowing which species provide the most relevant data can reduce the number of animals needed for testing.