gene knockout models

Why Use Gene Knockout Models in Toxicology?

Gene knockout models are crucial in toxicology because they help identify the genetic basis of susceptibility to toxicants. By observing the differences in toxicity between wild-type and knockout organisms, researchers can determine the role of specific genes in metabolizing toxins, repairing damage, or mediating immune responses. Such insights are invaluable for developing personalized medicine approaches and understanding species-specific differences in toxicology.

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