Sv40 Small T Antigen - Toxicology

Relevant Publications

Assessment of Residual Full-Length SV40 Large T Antigen in Clinical-grade Adeno-associated Virus Vectors Produced in 293T Cells.

Issue Release: 2023

A new T-antigen negative HEK293 cell line with improved AAV productivity.

Issue Release: 2023

Regulation of Virus Replication by BK Polyomavirus Small T Antigen.

Issue Release: 2023

Conservation of Importin α Function in Apicomplexans: Ivermectin and GW5074 Target Importin α and Inhibit Parasite Growth in Culture.

Issue Release: 2022

Long-read sequencing reveals complex patterns of wraparound transcription in polyomaviruses.

Issue Release: 2022

Isolation and immortalization of macrophages derived from fetal porcine small intestine and their susceptibility to porcine viral pathogen infections.

Issue Release: 2022

Molecular dissection on inhibition of Ras-induced cellular senescence by small t antigen of SV40.

Issue Release: 2022

Sustained AMPK Activation and Proline Metabolism Play Critical Roles in the Survival of Matrix-Deprived Transformed Cells.

Issue Release: 2021

Evaluating the Epithelial-Mesenchymal Program in Human Breast Epithelial Cells Cultured in Soft Agar Using a Novel Macromolecule Extraction Protocol.

Issue Release: 2021

Acitretin and Retinoic Acid Derivatives Inhibit BK Polyomavirus Replication in Primary Human Proximal Renal Tubular Epithelial and Urothelial Cells.

Issue Release: 2021

Phenotypic Characterization of Immortalized Chondrocytes from a Desbuquois Dysplasia Type 1 Mouse Model: A Tool for Studying Defects in Glycosaminoglycan Biosynthesis.

Issue Release: 2021

Design and Testing of Vector-Producing HEK293T Cells Bearing a Genomic Deletion of the SV40 T Antigen Coding Region.

Issue Release: 2020

Immortalized normal human lung epithelial cell models for studying lung cancer biology.

Issue Release: 2020

Synovial Cell Migration is Associated with B Cell Activating Factor Expression Increased by TNFα or Decreased by KR33426.

Issue Release: 2020

STRIPAK directs PP2A activity toward MAP4K4 to promote oncogenic transformation of human cells.

Issue Release: 2020

A pilot study of alternative TrkAIII splicing in Merkel cell carcinoma: a potential oncogenic mechanism and novel therapeutic target.

Issue Release: 2019

Influence of gene modification in biological behaviors and responses of mouse lung telocytes to inflammation.

Issue Release: 2019

Radiation-Induced Malignant Transformation of Preneoplastic and Normal Breast Primary Epithelial Cells.

Issue Release: 2019

A fail-safe system to prevent oncogenesis by senescence is targeted by SV40 small T antigen.

Issue Release: 2019

Serum IgG antibodies from healthy subjects up to 100 years old react to JC polyomavirus.

Issue Release: 2018

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