Threshold Of Toxicological Concern (ttc) - Toxicology

Relevant Publications

Update to RIFM fragrance ingredient safety assessment, 2-methyl-4-phenylbutyraldehyde, CAS Registry Number 40654-82-8.

Issue Release: 2024

The fate of Alternaria toxin tenuazonic acid (TeA) during the processing chain of wheat flour products and risk control strategies for mycotoxins.

Issue Release: 2024

Commentary: Value of information case study strongly supports use of the Threshold of Toxicological Concern (TTC).

Issue Release: 2024

Safety assessment of Paeonia lactiflora root extract for a cosmetic ingredient employing the threshold of toxicological concern (TTC) approach.

Issue Release: 2024

Fluorinated liquid-crystal monomers in infant formulas and implication for health risk.

Issue Release: 2024

RIFM fragrance ingredient safety assessment, 4-(4-methyl-3-penten-1-yl)-2(5H)-furanone, CAS Registry Number 61315-75-1.

Issue Release: 2024

Detailed aggregate exposure analysis shows that exposure to fragrance ingredients in consumer products is low: Many orders of magnitude below thresholds of concern.

Issue Release: 2024

Scientific Guidance on the criteria for the evaluation and on the preparation of applications for the safety assessment of post-consumer mechanical PET recycling processes intended to be used for manufacture of materials and articles in contact with food.

Issue Release: 2024

The cliff-edge of toxicological concern: highlighting the potential issues of an over-reliance on \"less-than-lifetime\" thresholds.

Issue Release: 2024

Establishment of a Threshold of Toxicological Concern for Pharmaceutical Intermediates based on Historical Repeat-Dose Data and its Application in Setting Health Based Exposure Limits.

Issue Release: 2024

Computational framework for identifying and evaluating mutagenic and xenoestrogenic potential of food additives.

Issue Release: 2024

Update to RIFM fragrance ingredient safety assessment, 4-hexen-1-ol, 5-methyl-2-(1-methylethenyl)-, CAS Registry Number 58461-27-1.

Issue Release: 2024

Flavouring Group Evaluation 413 (FGE.413): Naringenin.

Issue Release: 2024

Flavouring Group Evaluation 80, Revision 2 (FGE.80Rev2): Consideration of alicyclic, alicyclic-fused and aromatic-fused ring lactones evaluated by the JECFA (61st and 82nd meetings) structurally related to an aromatic lactone evaluated in FGE.27.

Issue Release: 2024

Use of the Threshold of Toxicological Concern (TTC) Approach as an Alternative Tool for Regulatory Purposes: A Case Study with an Inert Ingredient used in Pesticide Products.

Issue Release: 2024

Lack of genotoxicity potential and safety assessment of 4-(2-hydroxyethyl) morpholine present as an impurity in pharmaceuticals and nutritional supplements.

Issue Release: 2023

Uptake of selected antiretrovirals by pepper (Capsicum annum), radish (Raphanus sativus), and ryegrass (Lolium perenne) grown on two contrasting soils and fertilized with human urine-derived fertilizers.

Issue Release: 2023

FEMA GRAS assessment of natural flavor complexes: Sage oil, Orris Root Extract and Tagetes Oil and related flavoring ingredients.

Issue Release: 2023

Unraveling biomarkers of exposure for tenuazonic acid through urinary metabolomics.

Issue Release: 2023

Analysis of volatile organic compounds and potential odour compounds in food contact paperboard using headspace two-dimensional GC-QTOF-MS.

Issue Release: 2023

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What are Peroxidases?

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Threshold Of Toxicological Concern (ttc) - Toxicology

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