X. chris Le - Toxicology

Author Information

X. Chris Le is a distinguished researcher affiliated with the Department of Chemistry and the Division of Analytical and Environmental Toxicology at the University of Alberta, Edmonton, Canada. His work spans across the Faculty of Medicine and Dentistry, highlighting his interdisciplinary approach to analytical and environmental toxicology.

Research Contributions

Dr. X. Chris Le has made significant contributions to the field of analytical chemistry, with a focus on the development of diagnostic assays and the application of CRISPR technology. His recent work includes innovative approaches for the detection of SARS-CoV-2, employing CRISPR-Cas systems and novel amplification strategies. Additionally, he has explored the structural improvements of lateral flow assay devices and the discovery of arsenolipids using advanced mass spectrometry techniques. His research is pivotal in advancing diagnostic methodologies and understanding the environmental impacts of toxic substances such as mercury emissions.

Aliases

X. Chris Le is known by several aliases including X Chris Le, X. C. Le, X.\u2005chris Le, X C Le, X Le, Xc Le, and X.chris Le. These variations are often found in his publications and academic references.

Publication and Citation Metrics

Metric	Value
Citation Count	12,405
h-index	60
Paper Count	240

Publications:

On-Site Viral Inactivation and RNA Preservation of Gargle and Saliva Samples Combined with Direct Analysis of SARS-CoV-2 RNA on Magnetic Beads

DOI: 10.1021/acsmeasuresciau.1c00057

Year: 2022

The CRISPR-Cas toolbox for analytical and diagnostic assay development.

DOI: 10.1039/d1cs00098e

Year: 2021

CRISPR Technique Incorporated with Single-Cell RNA Sequencing for Studying Hepatitis B Infection.

DOI: 10.1021/acs.analchem.1c02227

Year: 2021

Integrating Reverse Transcription Recombinase Polymerase Amplification with CRISPR Technology for the One-Tube Assay of RNA.

DOI: 10.1021/acs.analchem.1c03456

Year: 2021

CRISPR/Cas12a-mediated gold nanoparticle aggregation for colorimetric detection of SARS-CoV-2.

DOI: 10.1039/d1cc02546e

Year: 2021

Mapping Isoform Abundance and Interactome of the Endogenous TMPRSS2-ERG Fusion Protein by Orthogonal Immunoprecipitation–Mass Spectrometry Assays

DOI: 10.1016/j.mcpro.2021.100075

Year: 2021

Discovery and Identification of Arsenolipids Using a Precursor-Finder Strategy and Data-Independent Mass Spectrometry

DOI: 10.1021/acs.est.0c07175

Year: 2021

Recent advances in structural improvements and chemicalmodifications of lateral flow assay devices

DOI: 10.1360/ssc-2021-0025

Year: 2021

Reduction of mercury emissions from anthropogenic sources including coal combustion.

DOI: 10.1016/j.jes.2020.11.002

Year: 2021

CRISPR technology incorporating amplification strategies: molecular assays for nucleic acids, proteins, and small molecules†

DOI: 10.1039/d0sc06973f

Year: 2021

How Can Lithium Toxicity be Prevented?

What Is the Significance of Studying Microstructural Changes in Toxicology?

How Does Antibiotic Misuse Lead to Toxicity?

How Does Human Error Impact Toxicological Studies?

What Are the Current Challenges in Biomaterials Toxicology?

Can Dehydration Interact with Environmental Toxins?

Why is Water Treatment Important in Toxicology?

What are Heat Shock Proteins?

What Are Common Toxic Agents Associated with Multi-Organ Failure?

How Do Toxins Affect Serine Proteases?

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