Why is Urine Alkalinization Important in Toxicology?
Urine alkalinization is crucial because it can significantly enhance the elimination of specific toxins and drugs from the body. Substances such as salicylates, phenobarbital, and methotrexate are examples of compounds whose excretion can be increased through urine alkalinization. By increasing the urine pH, these substances become more ionized and less likely to be reabsorbed in the renal tubules, facilitating their elimination.
