Are There Any Drugs That Target Vasopressin V2 Receptors?
Yes, there are drugs known as vasopressin receptor antagonists, or "vaptans," that specifically target V2 receptors. These drugs, such as tolvaptan and conivaptan, are used to treat conditions like the syndrome of inappropriate antidiuretic hormone secretion (SIADH) and heart failure. By blocking V2 receptors, these drugs promote water excretion without affecting sodium levels, thus helping to correct hyponatremia.
