Are There Any Limitations to Subcutaneous Administration?
Despite its advantages, there are some limitations to SC administration:
Limited Volume: The subcutaneous space can only hold a limited volume of fluid, which may not be sufficient for high-dose studies. Local Reactions: There may be local irritation or tissue damage at the injection site, which could influence study results. Species Differences: The absorption rate and effects of substances can vary significantly between different species, complicating the extrapolation of data from animal studies to humans.