Are There Any Limitations to Using Opioid Antagonists?
Although opioid antagonists are effective, they do have some limitations. One major limitation is their short duration of action. For instance, Naloxone may need to be administered multiple times to address the effects of long-acting opioids. Additionally, in cases of severe intoxication with high-potency opioids like fentanyl, higher doses of Naloxone may be required.