age and sex

Are there sex-specific differences in susceptibility to toxicants?

Yes, there are notable sex-specific differences in susceptibility to toxicants. For example, females are generally more susceptible to the toxic effects of certain pharmaceuticals and environmental toxins, possibly due to differences in enzyme activity. Conversely, males may be more prone to occupational exposures and their associated toxicities due to traditionally higher engagement in industries involving hazardous substances. Additionally, reproductive health can be uniquely affected; for instance, teratogens can specifically impact pregnant women and their developing fetuses.

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