Are There Specific Tissues More Susceptible to CAD Toxicity?
Yes, certain tissues are more susceptible to CAD toxicity due to their lipid-rich nature or high rates of drug exposure. The liver is particularly vulnerable as it is the primary site of drug metabolism. Similarly, the central nervous system can be affected due to the lipophilic nature of CADs, which allows them to easily cross the blood-brain barrier. Other affected tissues include the kidneys and lungs, where drug accumulation can lead to significant damage.
