To mitigate the risk of pyrazinoic acid-induced toxicity, several strategies can be employed. Dose adjustments based on body weight and renal function may be necessary, especially in populations such as the elderly or those with pre-existing liver disease. Additionally, regular monitoring of liver function and patient education on the signs of hepatotoxicity can aid in early detection and intervention. In some cases, alternative treatment regimens may be considered for patients at high risk of adverse effects.
