Monitoring the levels of pyrazinoic acid in patients can be crucial for preventing toxicity. This is typically achieved through regular liver function tests, which measure serum levels of liver enzymes such as alanine aminotransferase (ALT) and aspartate aminotransferase (AST). Elevated levels may indicate liver stress or damage. In some cases, therapeutic drug monitoring (TDM) of pyrazinoic acid itself may be employed to adjust drug dosages and minimize adverse effects.
