Therapeutic approaches to address oxidized LDL focus on both reducing its formation and mitigating its effects. Statins, a class of drugs used to lower cholesterol, can decrease the availability of LDL for oxidation. Other potential therapies include antioxidants like vitamin E and polyphenols, which may directly reduce oxidative stress. Experimental treatments targeting specific pathways involved in oxLDL formation and macrophage uptake are also being explored in the context of atherosclerosis treatment.