Can Adenylyl Cyclase Be Targeted for Therapeutic Interventions?
Given its central role in signaling pathways, adenylyl cyclase is a potential target for therapeutic interventions aimed at mitigating toxin effects. Inhibitors of adenylyl cyclase, such as SQ22536, can be used to prevent excessive cAMP production in cases of toxin exposure. Similarly, modulating GPCR activity with antagonists or inverse agonists can indirectly regulate adenylyl cyclase activity, offering another avenue for intervention.