Can Thrombin Be a Target for Anticoagulant Therapy?
Yes, thrombin is a common target for anticoagulant therapy. Drugs such as direct thrombin inhibitors (e.g., dabigatran) are designed to inhibit thrombin activity and are used to prevent and treat thromboembolic disorders. These medications must be carefully monitored to avoid the risk of bleeding, a potential toxicological concern associated with their use.
