The accuracy of POCT in toxicology can vary depending on the type of test and the substance being detected. Immunoassays, for example, are generally less specific than laboratory-based methods and may produce false positives or false negatives. However, advancements in technology are continually improving the sensitivity and specificity of these tests. Confirmatory testing using more precise methods like Gas chromatography-mass spectrometry (GC-MS) is often recommended to validate POCT results.