Chronic toxicity studies typically involve [animal models]() to simulate long-term human exposure. The substance is administered through various routes (oral, inhalation, dermal) to assess its effects. Parameters such as [body weight](), [food consumption](), [clinical signs](), and [mortality]() are monitored. At the end of the study, [histopathological examinations]() are conducted to identify any histological changes in tissues and organs.
