In toxicology, ESCs serve as a powerful model for evaluating the toxicity of chemicals and drugs. They can be differentiated into specific cell types, such as neurons, cardiomyocytes, or hepatocytes, which are then exposed to potential toxins. Observing the effects on these cells helps in understanding the toxicological impact on human tissues. This method is especially useful for studying developmental toxicity, as ESCs can mimic early embryonic development stages.