Genetic toxicology studies typically involve a series of in vitro and in vivo tests. In vitro tests, such as the Ames test, are conducted outside a living organism, often in cell cultures, to quickly assess the mutagenic potential of a substance. In vivo tests involve living organisms, such as rodents, to observe the effects of a substance on a whole organism's genetic material. These studies help determine the dose-response relationship and the mechanism of genetic damage.