Several standard tests are used in genetic toxicology to evaluate the potential of substances to cause genetic damage. These include:
Ames Test: A bacterial assay that detects mutations in Salmonella typhimurium or Escherichia coli. Chromosomal Aberration Test: Evaluates structural changes in chromosomes of cultured cells. Micronucleus Test: Detects chromosomal fragments or whole chromosomes that are not incorporated into the nucleus during cell division. Comet Assay: Measures DNA strand breaks in individual cells.