How are Soluble Compounds Metabolized and Excreted?
Soluble compounds are metabolized primarily in the liver through enzymatic processes that convert them into more water-soluble metabolites. These metabolites are then excreted from the body through the kidneys in urine or through bile in feces. The efficiency of these metabolic and excretory processes affects the overall toxicity of the compound. Some metabolites can be more toxic than the parent compound, a phenomenon known as bioactivation.