There are several strategies to make chemical syntheses less hazardous:
Use of Safer Solvents: Replacing toxic solvents with non-toxic or biodegradable alternatives. Alternative Pathways: Developing alternative chemical pathways that avoid the formation of hazardous intermediates. Green Catalysis: Employing catalysts that are non-toxic and more selective, thus reducing waste and unwanted side products. Atom Economy: Designing syntheses that maximize the incorporation of materials used in the final product, thereby reducing waste. Inherent Safety: Creating chemical processes that are inherently safer by design, such as using lower temperatures and pressures.