Management of fibrate toxicity involves both preventive and responsive strategies:
Monitoring: Regular monitoring of liver and kidney function tests, as well as lipid levels, can help in early detection of adverse effects. Patient Education: Educating patients about the potential signs of toxicity, such as muscle pain or weakness, can lead to prompt reporting and intervention. Dosage Adjustments: Adjusting doses based on renal function and the presence of side effects can help minimize risk. Alternative Therapies: In cases of intolerance or significant side effects, switching to alternative lipid-lowering agents like niacin or omega-3 fatty acids might be considered.
