How Can Pharmacokinetics Aid in the Development of Antidotes?
By analyzing the pharmacokinetics of a toxin, researchers can identify critical points in its ADME processes that can be targeted by antidotes. For instance, inhibiting specific metabolic pathways can prevent the formation of toxic metabolites, while enhancing excretion can speed up toxin clearance. Understanding the PK profile of toxins is thus pivotal in designing effective antidotes and treatment protocols.