To minimize the risk of exceeding the therapeutic dose, healthcare providers must ensure accurate prescribing and dispensing practices. This includes thorough patient assessment, consideration of all influencing factors, and using tools like pharmacokinetic calculations to tailor dosing. Educating patients about their medications, including potential side effects and the importance of adherence to prescribed regimens, is also crucial. Regular monitoring and follow-up can help detect early signs of toxicity, allowing for timely dose adjustments.