therapeutic dose

How is the Therapeutic Dose Determined?

The determination of a therapeutic dose involves extensive research and clinical trials. Initially, preclinical studies are conducted using animal models to assess the drug's pharmacokinetics and pharmacodynamics. Subsequently, clinical trials involving human subjects are performed, typically in three phases, to evaluate the drug's safety, efficacy, and optimal dosing. The results from these trials help establish the therapeutic index, which is the ratio between the toxic dose and the therapeutic dose.

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