How Can Variability be Minimized in Toxicological Testing?
To minimize variability in toxicological testing, researchers can standardize experimental conditions, use genetically homogeneous animal models, and apply statistical methods to account for variability. Human studies may use stratification to analyze subgroups separately, ensuring that differences in response due to known variables are considered. Additionally, incorporating advanced computational models can help predict variability and improve the extrapolation of data from animal models to humans.
