How Do 2D Cultures Contribute to Regulatory Toxicology?
In regulatory toxicology, 2D cell cultures are extensively used for routine testing of chemicals and drugs to comply with safety regulations. They provide a rapid assessment of acute toxicity and help in assessing dose-response relationships. Organizations like the FDA and EPA often rely on data from 2D cultures to make preliminary safety assessments before moving to animal studies or other more costly and complex testing methods.