How Do Drug Interactions Influence Warfarin Resistance?
Warfarin is known for its extensive interactions with other medications, which can either potentiate or diminish its effect. Drugs that induce CYP2C9, such as rifampin, can increase warfarin metabolism, leading to reduced anticoagulant effect and perceived resistance. On the other hand, inhibitors like amiodarone can increase warfarin levels, raising the risk of bleeding. Careful management and monitoring are essential to avoid these interactions.
