The interaction between the duration and frequency of exposure is complex and can influence the overall toxic effect. For example:
An acute, high-dose exposure may cause immediate and severe effects, while the same dose spread over a longer period may be less harmful. Chronic exposure to low doses can lead to bioaccumulation and long-term health issues, such as cancer or organ damage. Intermittent exposure may allow the body to recover between exposures, potentially reducing the overall toxic impact compared to continuous exposure.
