The age-related factors influence how an organism absorbs, distributes, metabolizes, and excretes toxic substances. Metabolic rates, immune system maturity, and organ function differ significantly between neonates, children, adults, and the elderly. For instance, neonates and infants have immature liver and kidney functions, making them more vulnerable to certain chemicals. In contrast, the elderly may have reduced detoxification capacity due to age-related decline in organ function.
