The most significant health concern associated with furanocoumarins is their potential to cause phototoxicity. When skin exposed to furanocoumarins is subjected to ultraviolet (UV) light, it can lead to photodermatitis, characterized by redness, swelling, and even blistering. This condition is often referred to as "lime disease" when caused by exposure to lime juice. The interaction with UV light can also increase the risk of skin cancer over time.
