In the realm of toxicology, hypoglycemic coma is frequently caused by the excessive intake of hypoglycemic agents, such as insulin or oral antidiabetic drugs. These substances lower blood glucose levels. Overdose, whether accidental or intentional, can lead to dangerously low blood sugar levels, resulting in a coma. Other substances, like alcohol or certain medications, can also contribute to hypoglycemia by suppressing gluconeogenesis or enhancing insulin action.