Genetic differences play a crucial role in shaping individual responses to toxic substances. Polymorphisms in genes responsible for the biotransformation of toxins can lead to variations in enzyme activity. For example, individuals with certain genetic variants may either detoxify a substance rapidly, reducing its harmful effects, or accumulate the toxin, leading to increased toxicity. Pharmacogenomics is an emerging field that studies these genetic variations to predict individual responses to drugs and toxicants. By understanding a personâs genetic makeup, healthcare providers can tailor treatments and preventive measures to reduce toxic risk.
