How do genetic polymorphisms affect toxin metabolism?
Genetic polymorphisms can lead to differences in the expression or function of enzymes involved in the metabolism of toxic substances. For instance, polymorphisms in genes encoding for cytochrome P450 enzymes can result in altered drug metabolism rates, impacting the toxicity and efficacy of pharmaceuticals. Individuals with certain polymorphisms may metabolize toxins more slowly or quickly, affecting their susceptibility to adverse effects.
