How Do Glycosidases Influence Toxicological Processes?
Glycosidases can affect toxicological processes through their ability to modify glycosylated compounds. Many toxicants and drugs undergo glycosylation, a process that often increases their solubility and facilitates excretion. Glycosidases can reverse this modification, potentially leading to the activation of pro-toxins or pro-drugs, thereby influencing their toxicity and therapeutic efficacy. Additionally, by altering glycoconjugates on cell surfaces, glycosidases can affect cell signaling and immune responses.
